Sun. Jul 21st, 2019

Enzymes Responsible For Brain and Muscle Disorders

Muscle Disorders

Brain disorders are a great deal that can cause complications affecting a lot of actions of the human body. It may finally lead to physical disorders and death which is why it should not be taken lightly. Yet, it is still hard to find treatments for such disorders due to the sensitivity of the brain for any treatments or surgeries.

However, a new study conducted by a team of scientists at the St. Jude Children’s Research Hospital were able to show a new breakthrough for these disorders. The study shows two main enzymes ULK1 and ULK2, which are responsible for cell breakdown. These two enzymes as they break cell structures they produce different proteins in the body that are toxic. The large number of toxic proteins causes death of cells from the brain and muscles.

Accordingly, the study reveals that this might be the cause for muscle and brain disorders that affects humans. The main diseases caused by such phenomena are the inclusion body myopathy (IBM), amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

The study was led by PhD holder, Mondira Kundu who is an associate member of the St. Jude Department of Pathology. He published his study and results in the Molecular Cell journal.

The study also suggests that there might be a way to control the production of the enzyme and the breakdown of cell structures. Accordingly, being able to control this biological step will help us reduce the spread of these diseases and help keep humans safer.