According to the latest research, the pharmaceutical industry is highlighting the usage of nanoparticles. The 4th Annual Peptide Drug Design and Delivery Summit, August 27 -29 in Philadelphia, concentrated on the several challenges and merits of incorporation of these molecules into therapies. According to reports, the medical application of nanotechnology in the pharmaceutical and medical industries vary from drug delivery, microfluidics, microarray tests, biosensors and tissue engineering. Nanomaterials range from the size of 1 to 100 nm. In comparison to the traditional therapeutic molecules, these molecules move freely in the human body. Nanomedicine is an emerging field of research and scientists are drawing concentrated efforts in designing nanomaterials necessary to deliver therapeutic agents to targeted sites in a more controlled manner. Michael Mitchell of the University of Pennsylvania is working on designing biomaterials in order to make the existing therapies safer and more effective for patients. In order to achieve this, molecules are encapsulated with nanomaterials which ionize upon entry into target cells. Furthermore, the lipid-like molecules used for encapsulated originate from a library created by Michael-addition chemistry. Experts allege this as an important reason to easily screen molecules effective at targeting cancer cells. In another example, Starpharama is using nanoparticles in clinical trials which use DEP® dendrimer product, a nanoparticle which contains additional molecules for drug delivery. The technology helps in achieving covalent bonding in order to conjugate small molecule proteins and targets moieties within commercial manufacturing standards of cGMP. The results showed improvements in pharamacokinetics, in addition to decreasing the cytotoxicity of therapeutic molecules. Further reports allege the company is exploring in using imaging in nanoparticle therapeutics and studying the combination of nanoparticle therapies.
Tags : drug delivery, microfluidics, microarray tests, biosensors, tissue engineering,